專家

曹林
職務:常務副院長
職稱:醫(yī)學博士、北大腫瘤醫(yī)院客座教授
專長:腫瘤學博士,河北一洲腫瘤醫(yī)院常務副院長,北大腫瘤醫(yī)院客座教授。對國內(nèi)外腫瘤臨床診療、腫瘤的發(fā)生機理、腫瘤分子診斷、耐藥機理方面的進展有深入研究,尤為擅長腫瘤綜合治療。
教育經(jīng)歷
1986年畢業(yè)于中國人民解放軍第四軍醫(yī)大學獲醫(yī)學學士學位,2003年赴英國留學深造,2007年獲英國阿伯丁大學腫瘤學博士學位,2008年至2012年在美國加州大學戴維斯分校薩克拉門拖醫(yī)療中心干細胞移植中心完成博士后工作。
工作經(jīng)歷
在解放軍309醫(yī)院血液腫瘤專業(yè)副主任醫(yī)師。后任解放軍309醫(yī)院醫(yī)療科長、醫(yī)務部副主任等職務。2012年至2017年在英國阿伯丁大學醫(yī)學研究院從事腫瘤耐藥及轉(zhuǎn)移機理的研究。2010年獲聘北京大學腫瘤醫(yī)院客座教授。2017年在河北一洲腫瘤醫(yī)院擔任常務副院長。
診療特長
從事臨床、科研、醫(yī)院管理38年,積累了豐富經(jīng)驗,對國內(nèi)外腫瘤臨床診療、腫瘤的發(fā)生機理、腫瘤分子診斷、耐藥機理方面的進展有深入研究,尤為擅長腫瘤綜合治療。特別是在腫瘤轉(zhuǎn)移及耐藥的機理研究方面有較高的造詣,對腫瘤的基因特點與預后的關(guān)系有豐富經(jīng)驗。在國內(nèi)外學術(shù)期刊發(fā)表學術(shù)論文30余篇,其中國外雜志24篇。
學術(shù)論文
· Lin Cao, Jie Liu, Jin Pu, Gillian Milne, Mei Chen, Heping Xu, Alan Shipley, John V Forrester, Colin D McCaig, Noemi Lois, Polarized retinal pigment epithelium generates electrical signals that diminish with age and regulate retinal pathology, J Cell Mol Med 2018 Nov;22 (11): 5552-5564
· Cao L, Liu J, Pu J, Collinson JM, Forrester JV, McCaig CD, Endogenous bioelectric currents promote differentiation of the mammalian lens, J Cell Physiol. 2017 Jun 29. doi: 10.1002/jcp.26074. [Epub ahead of print]
· Yang, B., Cao, L., Liu, J., Xu, Y., Milne, G., Chan, W., Heys, SD., McCaig, CD. & Pu, J. (2015). Low expression of chloride channel accessory 1 predicts a poor prognosis in colorectal cancer. Cancer. 2015 May 15; 121(10): 1570–1580.
· Jin Pu, Lin Cao, Colin D McCaig (2015). Physiological extracellular electrical signals guide and orient the polarity of gut epithelial cells, Tissue Barriers 02/2015; 3(3):e1037417.
· Lin Cao, Colin D McCaig, Jin Pu. Extracellular electric signals regulate neuroblast behaviours in adult brain (2015), Archives of Stem Cells & Research.
· Cao L, Pu J, Scott HR, Ching J, McCaig CD (2015). Endogenous electrical signals in brain promote chain migration of neuroblasts through up-regulation of the purinergic receptor P2Y1. Stem Cell Rev. 2015 Feb;11(1):75-86.
· Cao L, McCaig CD, Scott HR, Zhao SW, Milne G, Clevers H, Zhao M, Pu J (2014). Polarizing intestinal epithelial cells electrically through Ror2. Journal of Cell Science. 127(Pt 15):3233-9.
· Cao L, Wei D, Reid B, Zhao S, Pu J, Pan T, Yamoah E, Zhao M (2013). Endogenous
electric currents might guide rostral migration of neuroblasts. EMBO Rep 14(2):184-
90. (This paper was highlighted as hot off the press and cover image).
· Yang B, Cao L*, Liu B, McCaig CD, Pu J (2013). The transition from proliferation to
differentiation in colorectal cancer is regulated by the calcium activated chloride channel A1. PLoS One 8(4):e60861. (*Co-first author).
· Vu Tran V, Zhang XD, Cao L, Li HQ, Lee BJ, Chen W, Zhao M (2013). Electrically increase transepithelial potentials -- targeting Na+/K+ pumps using synchronized electrical modulation. PLoS One 8(4):e61509.
· Zhao M, Chalmers L, Cao L, Vieira AC, Mannis M, Reid B (2012). Electrical signalling in control of ocular cell behaviors. Prog Retin Eye Res 31(1):65-88.
· Cao L, Graue-Hernandez EO, Tran V, Reid B, Pu J, Mannis MJ, Zhao M (2011).
Down-regulation of PTEN at corneal wound sites accelerates wound healing through increased cell migration. Invest Ophthalmol Vis Sci 52(5): 2272-2278.
· Cao L, Pu J, Zhao M (2011). GSK-3β is essential for physiological electric fields directed Golgi polarization. Cell Mol Life Sci 68(18):3081-93.
· Vieira AC, Reid B, Cao L, Mannis MJ, Schwab JR, Zhao M (2011). Ionic components of electric current at rat corneal wounds. PLoS One 6(2):e17411.
· Reid B, Vieira AC, Cao L, Mannis MJ, Schwab IR, Zhao M (2011). Specific ion fluxes generate cornea wound electric currents. Commun Integr Biol 4(4):462-5.
· Cao L, Zhang XD, Liu X, Chen TY, Zhao M (2010). Chloride channels and transporters in human corneal epithelium. Exp Eye Res 90(6):771-9.
· Tai G, Reid B, Cao L, Zhao M (2009). Electrotaxis and wound healing: experimental methods to study electric fields as a directional signal for cell migration. Methods
Mol Biol 571:77-97.
· Pu J, McCaig CD, Cao L, Zhao ZQ, Segall JE, Zhao M (2007). Epidermal growth factor receptor signaling is essential for electric field directed migration of breast cancer cells. J Cell Sci 120(Pt 19):3395-403.
· 解傳濱;楊濤;王子申;方春鋒;徐壽平;曹林;曲寶林;質(zhì)子調(diào)強放療技術(shù)與2種光子旋轉(zhuǎn)調(diào)強放療技術(shù)在全中樞照射中的劑量學比較,醫(yī)療衛(wèi)生裝備 2021年05期
· 方春峰,候俊,徐壽平,楊濤,曲寶林,曹林,朱龍林,解東,繼達悅;質(zhì)子治療系統(tǒng)原理及其應用,中國醫(yī)學裝備,2021年4月,第18卷第4期
· 楊濤,曲寶林,徐壽平,解傳濱,徐偉,龔璇,曹林;IBA質(zhì)子筆形束掃描系統(tǒng)束流性能驗收測試,中華放射腫瘤學雜志 2020-12-15
· 楊濤,徐壽平,解傳濱,龔璇,徐偉,曲寶林,王子申,方春鋒,曹林;前列腺癌質(zhì)子調(diào)強與光子容積旋轉(zhuǎn)調(diào)強放療計劃質(zhì)量評估[J].中華放射醫(yī)學與防護雜志,2020,40(1):19-25
· 徐偉;楊濤;解傳濱;曲寶林;曹林;王子申;宋圓圓;方春鋒;徐壽平;質(zhì)子點掃描技術(shù)與光子Tomotherapy在前列腺癌應用中的劑量學比較,中國醫(yī)學物理學雜志2019年 第10期
科研課題(國外)
· Mechanisms of chemoresistance in solid tumours.
· Electrical control of retinal pigment epithelium and PEDF secretion: a new focus for treating age-related macular degeneration,
· The response of astrocytes to extracellular electrical signals (EES): Friend or Foe for CNS wound repair?
· Controlling Brain Tumours Electrically,
· SULSA Postdoctoral Exchange Scheme.
· A functional role for the transepithelial potential difference in cancer metastasis? -----Identification of electrically-regulated metastatic genes in breast cancer,